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A new class of quadruplex DNA-binding nickel Schiff base complexes

Pham, Son Q T; Assadawi, Nawal M O; Wells, Jadon; Sophocleous, Reece; Davis, Kimberley J; Haibo, Yu; Sluyter, Ronald; Dillon, Carolyn; Kelso, Celine; Beck, Jennifer; Willis, Anthony


We have prepared six new nickel Schiff base complexes via reactions of substituted benzophenones with different diamines in the presence of nickel(II). These new complexes were then reacted with 1-(2-choroethyl)piperidine to afford a further six novel nickel(II) Schiff base complexes bearing pendant ethylpiperidine groups. The complexes bearing the ethylpiperidine moieties had greater solubility in water, and were therefore suitable for use in DNA binding experiments. ESI mass spectra of...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
Source: Dalton Transactions
DOI: 10.1039/d0dt00319k


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