Skip navigation
Skip navigation

Synthesis and kinetic testing of tetrahydropyrimidine-2-thione and pyrrole derivatives as inhibitors of the metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa

Hussein, Waleed M; Fatahala, Samar; Mohamed, Zainab M; McGeary, Ross Peter; Schenk, Gerhard; Ollis, David; Mohamed, Mosaad S.

Description

Metallo-β-lactamases (MBLs), produced by an increasing number of bacterial pathogens, facilitate the hydrolysis of many commonly used β-lactam antibiotics. There are no clinically useful antagonists against MBLs. Two sets of tetrahydropyrimidine-2-thion

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/20927
Source: Chemical Biology and Drug Design
DOI: 10.1111/j.1747-0285.2012.01440.x

Download

File Description SizeFormat Image
01_Hussein_Synthesis_and_kinetic_testing_2012.pdf1.78 MBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator