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Resolution and improved synthesis of (±)-arsenicin A: a natural adamantane-type tetraarsenical possessing strong anti-acute promelocytic leukemia cell line activity

Lu, Di; Coote, Michelle; Ho, Junming; Kilah, Nathan; Lin, Ching-Yeh; Salem, Geoffrey; Weir, Michelle; Willis, Anthony; Wild, Stanley (Bruce); Dilda, Pierre J

Description

The resolution and improved synthesis of the naturally occurring, adamantane-type, tetraarsenical (±)-Arsenicin A is reported. The five-step synthesis of (±)-Arsenicin A from methylenebis(phenylarsinic acid) affords (±)-Arsenicin A as air-stable, color

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/20898
Source: Organometallics
DOI: 10.1021/om201180d

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