Jain , M; Velez, Jorge I; Acosta, Maria T; Palacio, LG; Balog, J.; Roessler, Erich; Pineda, David A; Londono, Ana C; Palacio, Juan David; Arbelaez, Andres; Arcos-Burgos, Mauricio (Oscar)
In previous studies of a genetic isolate, we identified significant linkage of attention deficit hyperactivity disorder (ADHD) to 4q, 5q, 8q, 11q and 17p. The existence of unique large size families linked to multiple regions, and the fact that these families came from an isolated population, we hypothesized that two-locus interaction contributions to ADHD were plausible. Several analytical models converged to show significant interaction between 4q and 11q (P<1 × 10-8) and 11q and 17p (P<1 ×...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.