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Trafficking and function of Maurer's clefts proteins and Maurer's clefts biogenesis

Zhang, Meng

Description

Plasmodium falciparum, the most lethal malaria parasite species for humans, vastly remodels the mature human red blood cell (RBC) upon invasion for its own survival. The severe pathology of P. falciparum infection is associated with the display of the major virulence protein, P. falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of the infected RBC and the subsequent cytoadhesion of infected cells in the microvasculature of host organs. This trafficking process is dependent on...[Show more]

CollectionsOpen Access Theses
Date published: 2020
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/206537
DOI: 10.25911/5f36686d83fd9
Access Rights: Open Access

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