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Limited Intravascular Coupling in the Rodent Brainstem and Retina Supports a Role for Glia in Regional Blood Flow

Kuo, Ivana; Chan-Ling, Tailoi; Wojcikiewicz, Richard J H; Hill, Caryl


Regional synaptic activity induces local increases in perfusion that are coupled to upstream vasodilation and improved blood flow. In the cerebral circulation, it has been proposed that astrocytes mediate the link between the initiating stimulus and local vasodilation through propagated intracellular calcium waves. In the systemic circulation the mechanism by which local vasodilation triggers upstream alterations in blood flow involves electrotonic propagation of hyperpolarization via...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Comparative Neurology
DOI: 10.1002/cne.21873


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