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P value-driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses

Furuya-Kanamori, Luis; Xu, Chang; Lin, Lifeng; Doan, Tinh; Chu, Haitao; Thalib, Lukman; Doi, Suhail A R

Description

Objectives The aim of the study was to investigate the effect of number of studies in a meta-analysis on the detection of publication bias using P value-driven methods. Methods The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests to have asymmetry suggestive of publication bias were examined in 5,014 meta-analyses from Cochrane reviews. P values were also assessed in meta-analyses with varying number of studies, whereas symmetry was held constant. A...[Show more]

CollectionsANU Research Publications
Date published: 2020
Type: Journal article
URI: http://hdl.handle.net/1885/205642
Source: Journal of Clinical Epidemiology
DOI: 10.1016/j.jclinepi.2019.11.011

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