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Study of bacteriophage encoded glucosyltransferase (gtr) genes in Shigella flexneri serotype 1c

Parajuli, Pawan

Description

Shigella flexneri is the primary cause of bacillary dysentery or shigellosis in developing countries. S. flexneri serotype 1c is a novel serotype which is emerging as the most prevalent serotype in many developing nations. It has a unique and highly modified O-antigen structure comprising of at least two distinct O-antigen modifying glucosyltransferase gene clusters (gtrI and gtrIc) that adds two-glucosyl groups to the N-acetylglucosamine residue of O-antigen. These genes are encoded by two...[Show more]

CollectionsRestricted Theses
Date published: 2020
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/204862
DOI: 10.25911/5eeb43ca4a169
Embargoed until: 2021-04-18

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