Skip navigation
Skip navigation

Tc-99m-radiolabeled composites enabling in vivo imaging of arterial dispersal and retention of microspheres in the vascular network of rabbit lungs, liver, and liver tumors.

Stephens, Ross; Tredwell, Greg; Knox, Karen; Philip, Lee; King, David; Debono, Kelly; Bell, Jessica; Senden, Timothy; Tanudji, Marcel R; Winter, Jillean; Bickley, Stephanie A; Tapner, Michael J; Jones, Stephen


Purpose: Selective internal radiation therapy (SIRT) is an effective treatment option for liver tumors, using Y-90-loaded polymer microspheres that are delivered via catheterization of the hepatic artery. Since Y-90 is a beta emitter and not conveniently imaged by standard clinical instrumentation, dosimetry is currently evaluated in each patient using a surrogate particle, 99mTechnetium-labeled macroaggregated albumin (99mTc-MAA). We report a new composite consisting of 99mTc-labeled...[Show more]

CollectionsANU Research Publications
Date published: 2019-01-31
Type: Journal article
Source: International journal of nanomedicine
DOI: 10.2147/IJN.S187153
Access Rights: Open Access


File Description SizeFormat Image
01_Stephens_Tc-99m-radiolabeled_composites_2019.pdf12.13 MBAdobe PDFThumbnail

This item is licensed under a Creative Commons License Creative Commons

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator