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Increased Serum C-reactive Protein and Corpus Callosum Alterations in Older Adults

Cyprien, Fabienne; Courtet, Philippe; Maller, Jerome; Meslin, Chantal; Ritchie, K; Ancelin, Marie-Laure; Artero, Sylvaine


Chronic systemic low-grade inflammation is associated with aging, but little is known on whether age-related inflammation affects brain structure, particularly white matter. The current study tested the hypothesis that in older adults without dementia, higher serum levels of high-sensitivity C-reactive protein (hs-CRP) are associated with reduced corpus callosum (CC) areas. French community-dwelling subjects (ESPRIT study) aged 65 and older (N=101) underwent hs-CRP testing and structural...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
Source: Aging and Disease
DOI: 10.14336/AD.2018.0329
Access Rights: Open Access


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