Alzheimer's Environmental and Genetic Risk Scores are Differentially Associated With General Cognitive Ability and Dementia Severity
Purpose: We investigated the association of the Australian National University Alzheimer’s Disease Risk Index (ANU-ADRI) and an Alzheimer disease (AD) genetic risk score (GRS) with cognitive performance. Methods: The ANU-ADRI (composed of 12 risk factors for AD) and GRS (composed of 25 AD risk loci) were computed in 1061 community-dwelling older adults. Participants were assessed on 11 cognitive tests and activities of daily living. Structural equation modeling was used to evaluate the...[Show more]
|Collections||ANU Research Publications|
|Source:||Alzheimer Disease and Associated Disorders|
|01_Andrews_Alzheimer%27s_Environmental_and_2019.pdf||246.89 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.