Paramagnetic labelling of proteins and oligonucleotides for NMR
Paramagnetic effects offer a rich source of long-range structural restraints. Here we review current methods for site-specific tagging of proteins and oligonucleotides with paramagnetic molecules. The paramagnetic tags include nitroxide radicals and metal chelators. Particular emphasis is placed on tags suitable for site-specific and rigid attachment of lanthanide ions to macromolecules.
|Collections||ANU Research Publications|
|Source:||Journal of Biomolecular NMR|
|01_Su_Paramagnetic_labelling_of_2010.pdf||379.6 kB||Adobe PDF||Request a copy|
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