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Oncogenesis and cancer stem cells: current opinions and future directions

Cheng, Xiaoyu Y; O'Neill, Helen


There is increasing evidence to show that only a subset of cancer cells drives the growth and progression of a tumour. These cells share similar properties with normal stem cells and are termed 'cancer stem cells'. Cancer stem cells have been identified in acute myeloid leukaemia and in some solid tumours by their distinct expression of cell surface antigens. Their long-term, self-renewing capacity is thought to be a determining factor in the maintenance and regrowth of the tumour. Studies on...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Journal of Cellular and Molecular Medicine
DOI: 10.1111/j.1582-4934.2008.00664.x


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