Altered sodium currents in auditory neurons of congenitally deaf mice
Sodium currents are essential for action potential generation and propagation in most excitable cells. Appropriate tuning of these currents can be modulated both developmentally and in response to activity. Here we use a mouse model of congenital deafness (dn/dn- asymptomatic deafness associated with hair cell degeneration) to investigate the effect of lack of activity in the expression of Na+ currents in neurons from the medial nucleus of the trapezoid body (MNTB). Patch-clamp recordings show...[Show more]
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|Source:||European Journal of Neuroscience|
|01_Leao_Altered_sodium_currents_in_2006.pdf||2.9 MB||Adobe PDF||Request a copy|
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