Neuropsychological health in F-111 aircraft maintenance workers
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Schofield, Peter W; Gibson, Richard; Tavener, Meredith; Attia, John R; D'Este, Catherine; Guest, Maya; Brown, Anthony M; Lee, Stephen J; Horsley, Keith; Harrex, Warren; Ross, James; Whitworth, Judith; Henderson, A Scott
Description
Objective: To contrast subjective and objective measures of neuropsychological health in F-111 aircraft Deseal/Reseal maintenance personnel, against two appropriate comparison groups. Methods: Exposed and comparison participants completed a postal questionnaire which included a validated memory questionnaire and additional questions relating to possible cognitive symptoms. They also underwent a comprehensive neuropsychological assessment and screening for a past or current disturbance of mood....[Show more]
dc.contributor.author | Schofield, Peter W | |
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dc.contributor.author | Gibson, Richard | |
dc.contributor.author | Tavener, Meredith | |
dc.contributor.author | Attia, John R | |
dc.contributor.author | D'Este, Catherine | |
dc.contributor.author | Guest, Maya | |
dc.contributor.author | Brown, Anthony M | |
dc.contributor.author | Lee, Stephen J | |
dc.contributor.author | Horsley, Keith | |
dc.contributor.author | Harrex, Warren | |
dc.contributor.author | Ross, James | |
dc.contributor.author | Whitworth, Judith | |
dc.contributor.author | Henderson, A Scott | |
dc.date.accessioned | 2015-12-07T22:20:57Z | |
dc.identifier.issn | 0161-813X | |
dc.identifier.uri | http://hdl.handle.net/1885/19814 | |
dc.description.abstract | Objective: To contrast subjective and objective measures of neuropsychological health in F-111 aircraft Deseal/Reseal maintenance personnel, against two appropriate comparison groups. Methods: Exposed and comparison participants completed a postal questionnaire which included a validated memory questionnaire and additional questions relating to possible cognitive symptoms. They also underwent a comprehensive neuropsychological assessment and screening for a past or current disturbance of mood. Multiple linear or logistic regression was conducted for each outcome using exposure group and potential confounders as explanatory variables. Results: There was a strong and consistent excess of self-reported cognitive problems among the exposed group relative to the comparison groups including a 2.8-4.3-fold increase in self-reported symptoms of forgetfulness, loss of concentration and difficulty finding the right word. On detailed neuropsychological testing, the exposed group performed significantly worse than comparisons on tests of psychomotor speed, executive functioning, and new learning/memory. These findings could not be accounted for by disturbances of mood or other potential confounders. Conclusions: There was a strong and consistent increase in self-reported cognitive problems among the exposed, and small but significant exposure-specific differences on objective tests of cognitive functioning. The findings are consistent with the development of adverse neuropsychiatric changes related to occupational exposure to solvents. | |
dc.publisher | Elsevier | |
dc.source | NeuroToxicology | |
dc.subject | Keywords: solvent; adult; airplane crew; article; automation; brain function; clinical assessment; cognitive defect; comparative study; concentration loss; control group; controlled study; female; human; learning; major clinical study; male; memory; memory disorder Air force maintenance personnel; Neuropsychological; Occupational exposure; Solvent | |
dc.title | Neuropsychological health in F-111 aircraft maintenance workers | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 27 | |
dc.date.issued | 2006 | |
local.identifier.absfor | 111799 - Public Health and Health Services not elsewhere classified | |
local.identifier.ariespublication | u9505948xPUB9 | |
local.type.status | Published Version | |
local.contributor.affiliation | Schofield, Peter W, Greater Western Area Health Service | |
local.contributor.affiliation | Gibson, Richard, Commonwealth Department of Veterans' Affairs | |
local.contributor.affiliation | Tavener, Meredith, Royal Newcastle Hospital | |
local.contributor.affiliation | Attia, John R, University of Newcastle | |
local.contributor.affiliation | D'Este, Catherine (use E7520), University of Newcastle | |
local.contributor.affiliation | Guest, Maya, University of Newcastle | |
local.contributor.affiliation | Brown, Anthony M, Commonwealth Department of Veterans' Affairs | |
local.contributor.affiliation | Lee, Stephen J, Hunter New England Area Health Service | |
local.contributor.affiliation | Horsley, Keith, Commonwealth Department of Veterans' Affairs | |
local.contributor.affiliation | Harrex, Warren, Commonwealth Department of Veterans' Affairs | |
local.contributor.affiliation | Ross, James, Commonwealth Department of Defence | |
local.contributor.affiliation | Whitworth, Judith, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Henderson, A Scott, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.startpage | 852 | |
local.bibliographicCitation.lastpage | 860 | |
local.identifier.doi | 10.1016/j.neuro.2006.02.002 | |
dc.date.updated | 2015-12-07T08:52:25Z | |
local.identifier.scopusID | 2-s2.0-33747182484 | |
Collections | ANU Research Publications |
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