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G alpha(z) Negatively Regulates Insulin Secretion and Glucose Clearance

Kimple, Michelle; Joseph, Jamie W; Bailey, Candice; Fueger, Patrick; Hendry, Ian; Newgard, Christopher; Casey, Patrick

Description

Relatively little is known about the in vivo functions of the α subunit of the heterotrimeric G protein Gz (Gαz). Clues to one potential function recently emerged with the finding that activation of Gαz inhibits glucose-stimulated insulin secretion in

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/19725
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M706481200

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