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Impact of the 23-valent pneumococcal polysaccharide vaccination in pregnancy against infant acute lower respiratory infections in the Northern Territory of Australia

Binks, Michael J.; Moberley, Sarah A.; Balloch, Anne; Leach, A. J.; Nelson, Sandra; Hare, Kim M.; Wilson, Cate; Nelson, Jane; Morris, Peter; Ware, Robert S.; Andrews, Ross


BackgroundIndigenous children in Australia's Northern Territory are densely colonised with the pneumococcus within weeks of birth antecedent to a high prevalence of acute lower respiratory infection (ALRI). We assessed the impact of the 23-valent pneumococcal polysaccharide vaccine (23vPPV) in pregnancy against infant ALRI in this setting.MethodsIn an open label, allocation concealed, outcome-assessor blinded, randomised controlled trial conducted in the Northern Territory of Australia, healthy...[Show more]

CollectionsANU Research Publications
Date published: 2018-05-16
Type: Journal article
Source: Pneumonia
DOI: 10.1186/s41479-018-0057-2
Access Rights: Open Access


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