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The Role of Homology and Orthology in the Phylogenomic Analysis of Metazoan Gene Content

Pett, Walker; Adamski, Marcin; Adamska, Maja; Francis, Warren R.; Eitel, Michael; Pisani, Davide; Worheide, Gert


Resolving the relationships of animals (Metazoa) is crucial to our understanding of the origin of key traits such as muscles, guts, and nerves. However, a broadly accepted metazoan consensus phylogeny has yet to emerge. In part, this is because the genomes of deeply diverging and fast-evolving lineages may undergo significant gene turnover, reducing the number of orthologs shared with related phyla. This can limit the usefulness of traditional phylogenetic methods that rely on alignments of...[Show more]

CollectionsANU Research Publications
Date published: 2019-01-28
Type: Journal article
Source: Molecular Biology and Evolution
DOI: 10.1093/molbev/msz013


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