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The merozoite-specific protein, TgGRA11B, identified as a component of the Toxoplasma gondii parasitophorous vacuole in a tachyzoite expression model

Ramakrishnan, Chandra; Walker, Robert A.; Eichenberger, Ramon M.; Hehl, Adrian B.; Smith, Nicholas

Description

The apicomplexan, Toxoplasma gondii, infects all warm-blooded animals as intermediate hosts but only felids as definitive hosts. Dense granule proteins are critical for the survival of Toxoplasma within host cells but, whilst these proteins have been studied intensively in tachyzoites, little is known about their expression in the coccidian stages in the cat intestine. Transcriptomic profiling indicates that two putative dense granule proteins, TgGRA11A and TgGRA11B, are expressed uniquely in...[Show more]

CollectionsANU Research Publications
Date published: 2017-05-17
Type: Journal article
URI: http://hdl.handle.net/1885/193745
Source: International Journal for Parasitology
DOI: 10.1016/j.ijpara.2017.04.001

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