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Mid Life Stress is associated with both up- and down-regulation of markers of humoral and cellular immunity

Dear, Keith; Ponsonby, Anne-Louise; Lucas, Robyn


Perception of stress with consequent activation of a neuroendocrine cascade causes changes in immune function that may be bi-directional, with alterations in basal levels of biological parameters outside the optimal range. In this cross-sectional study of 302 healthy persons (males 56.3%, females 43.7%) aged 41-46 years, higher stress levels, as assessed by questionnaire measures of recurrent and recent perceived stress, were associated with a 4-fold greater risk of having a high compared to...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Stress
DOI: 10.1080/10253890701379023


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