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Establishment of in vitro and in vivo anti-colon cancer efficacy of essential oils containing oleo-gum resin extract of Mesua ferrea

Asif, Muhammad; Yehya, Ashwaq H S; Dahham, Saad Sabbar; Mohamed, Shazmin Kithur; Shafaei, Armaghan; Ezzat, Mohammed Oday; Abdul Majid, Aman Shah; Oon, Chern Ein; Abdul Majid, Amin Malik Shah Bin

Description

Proven the great potential of essential oils as anticancer agents, the current study intended to explore molecular mechanisms responsible for in vitro and in vivo anti-colon cancer efficacy of essential oil containing oleo-gum resin extract (RH) of Mesua ferrea. MTT cell viability studies showed that RH had broad spectrum cytotoxic activities. However, it induced more profound growth inhibitory effects towards two human colon cancer cell lines i.e., HCT 116 and LIM1215 with an IC50 values of...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
URI: http://hdl.handle.net/1885/186778
Source: Biomedicine and Pharmacotherapy
DOI: 10.1016/j.biopha.2018.10.127
Access Rights: Open Access

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