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Association of Alzheimer's genetic loci with mild behavioral impairment

Andrews, Shea; Ismail, Zahinoor; Anstey, Kaarin; Mortby, Moyra


Mild behavioral impairment (MBI) describes the emergence of later‐life neuropsychiatric symptoms (NPS) as an at‐risk state for incident cognitive decline and dementia, and for some as a potential manifestation of prodromal dementia. How NPS mechanistically link to the development of mild cognitive impairment and Alzheimer's disease (AD) is not fully understood, with potential mechanisms including shared risk factors related to both NPS and cognitive impairment, or AD pathology promoting NPS....[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: American Journal of Medical Genetics, Part B: Neuropsychiatric
DOI: 10.1002/ajmg.b.32684


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