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Deletion of Ten-m3 Induces the Formation of Eye Dominance Domains in Mouse Visual Cortex

Merlin, Sam; Horng, Sam; Marotte, Lauren; Sur, Mriganka; Sawatari, Atomu; Leamey, Cathy


The visual system is characterized by precise retinotopic mapping of each eye, together with exquisitely matched binocular projections. In many species, the inputs that represent the eyes are segregated into ocular dominance columns in primary visual cortex (V1), whereas in rodents, this does not occur. Ten-m3, a member of the Ten-m/Odz/Teneurin family, regulates axonal guidance in the retinogeniculate pathway. Significantly, ipsilateral projections are expanded in the dorsal lateral geniculate...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Cerebral Cortex
DOI: 10.1093/cercor/bhs030


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