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Calcium spikes in basal dendrites of layer 5 pyramidal neurons during action potential bursts

Kampa, Bjoern; Stuart, Gregory J


Patch-clamp recording from dendrites has lead to a significant increase in our understanding of the mechanisms underlying signal integration and propagation in neurons. The majority of synaptic input to neurons, however, is made onto small-diameter dendrites, currently beyond the scope of patch-clamp recording techniques. Here we use both calcium and voltage imaging to investigate propagation of action potentials (APs) in fine basal dendrites of cortical layer 5 pyramidal neurons....[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Journal of Neuroscience
DOI: 10.1523/JNEUROSCI.3062-05.2006


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