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Cone Degeneration in Aging and Age-Related Macular Degeneration

Shelley, Elizabeth; Madigan, Michelle; Penfold, Philip; Natoli, Riccardo; Provis, Jan


Objective: To examine the morphological features of macular photoreceptors in histologically normal retina from normal donor eyes and eyes with age-related macu- lar degeneration (AMD). Methods: The macular region was excised from 18 donor eyes (aged 22-96 years) and cryosectioned. Sections were stained with hematoxylin-eosin or double immu- nolabeled using opsin antibodies or synaptic markers. Results: Three of 8 retinas studied in detail had AMD lesions; the remainder were histologically...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Archives of Ophthalmology
DOI: 10.1001/archophthalmol.2008.622


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