Skip navigation
Skip navigation

Lipid-related genetic polymorphisms significantly modulate the association between lipids and disability progression in multiple sclerosis

Zhang, Yan; Zhou, Yuan; van der Mei, Ingrid A. F.; Simpson, Steve; Ponsonby, Anne-Louise; Lucas, Robyn; Tettey, Prudence; Charlesworth, Jac C.; Kostner, Karam; Taylor, B. V.

Description

Objective To investigate whether lipid-related or body mass index (BMI)–related common genetic polymorphisms modulate the associations between serum lipid levels, BMI and disability progression in multiple sclerosis (MS). Methods The association between disability progression (annualised Expanded Disability Status Scale (EDSS) change over 5 years, ΔEDSS) and lipid-related or BMI-related genetic polymorphisms was evaluated in a longitudinal cohort (n=184), diagnosed with MS. We constructed a...[Show more]

CollectionsANU Research Publications
Date published: 2019-05-16
Type: Journal article
URI: http://hdl.handle.net/1885/180102
Source: Journal of Neurology, Neurosurgery & Psychiatry
DOI: 10.1136/jnnp-2018-319870
Access Rights: Open Access

Download

File Description SizeFormat  
Auslong_LipidGenetics_05092018.docx118.18 kBMicrosoft Word XML


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator