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Metabolite profiling identifies the mycotoxin alternariol in the pathogen Stagonospora nodorum

Tan, Kar-Chun; Trengove, Robert; Maker, Garth L.; Oliver, Richard Peter; Solomon, Peter


A recent comparative proteomics study identified the short-chain dehydrogenase (Sch1) as being required for asexual sporulation (Tan et al. Eukaryotic Cell 7:1916-1929, 2008). Metabolite profiling was undertaken on the mutant strains of Stagonospora nodorum lacking the Sch1 gene to help elucidate its role. Gas chromatography-mass spectrometry of the polar metabolites in the Sch1 mutants identified a secondary metabolite at a 200-fold greater concentration than observed in the wild-type strains....[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Metabolomics
DOI: 10.1007/s11306-009-0158-2


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