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Use of quantitative PCR to assess the efficacy of albendazole against Necator americanus and Ascaris spp. in Manufahi District, Timor-Leste

Vaz Nery, Susana; Qi, Jessica; Llewellyn, Stacey; Clarke, Naomi; Traub, Rebecca; Gray, Darren; Vallely, Andrew; Williams, Gail; Andrews, Ross M.; McCarthy, James; Clements, Archie

Description

Soil-transmitted helminths (STHs) including Ascaris lumbricoides, Necator americanus, Ancylostoma spp. and Trichuris trichiura are cause of significant global morbidity. To mitigate their disease burden, at-risk groups in endemic regions receive periodic mass drug administration using anthelmintics, most commonly albendazole and mebendazole. Assessing the efficacy of anthelmintic drugs is important for confirming that these regimens are working effectively and that drug resistance has not...[Show more]

CollectionsANU Research Publications
Date published: 2018-06-28
Type: Journal article
URI: http://hdl.handle.net/1885/176592
Source: Parasites and Vectors
DOI: 10.1186/s13071-018-2838-0
Access Rights: Open Access

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