Skip navigation
Skip navigation

Characterization of the opossum immune genome provides insights into the evolution of the mammalian immune system

Belov, Katherine; Sanderson, Claire; Deakin, Janine; Wong, Emily; Assange, Daniel; McColl, Kaighin A; Gout, Alex; de Bono, Bernard; Barrow, Alexander D; Speed, Terence P; Trowsdale, John; Papenfuss, Anthony T


The availability of the first marsupial genome sequence has allowed us to characterize the immunome of the gray short-tailed opossum (Monodelphis domestica). Here we report the identification of key immune genes, including the highly divergent chemokines, defensins, cathelicidins, and Natural Killer cell receptors. It appears that the increase in complexity of the mammalian immune system occurred prior to the divergence of the marsupial and eutherian lineages ∼180 million years ago. Genomes of...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Genome Research
DOI: 10.1101/gr.6121807


File Description SizeFormat Image
01_Belov_Characterization_of_the_2007.pdf1.16 MBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator