Ratnadiwakara, Madara; Rooke, Melissa; Ohms, Stephen; French, Hugh; Williams, Rohan; Li, Rachel; Zhang, Daohai; Lucas, Robyn; Blackburn, Anneke
Breast cancer is a complex disease, and approximately 30% of cases are considered to be hereditary or familial, with a large fraction of this being polygenic. However, it is difficult to demonstrate the functional importance of genes of small effect in population studies, and these genes are not always easily targeted for prevention. The SuprMam (suppressor of mammary tumour) breast cancer susceptibility alleles were previously identified as contributors to spontaneous mammary tumour...[Show more]
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