Skip navigation
Skip navigation
Open Research will be down for maintenance between 8:00 and 8:15 am on Tuesday, December 1 2020.

The SuprMam1 breast cancer susceptibility locus disrupts the vitamin D/ calcium/ parathyroid hormone pathway and alters bone structure in congenic mice

Ratnadiwakara, Madara; Rooke, Melissa; Ohms, Stephen; French, Hugh; Williams, Rohan; Li, Rachel; Zhang, Daohai; Lucas, Robyn; Blackburn, Anneke

Description

Breast cancer is a complex disease, and approximately 30% of cases are considered to be hereditary or familial, with a large fraction of this being polygenic. However, it is difficult to demonstrate the functional importance of genes of small effect in population studies, and these genes are not always easily targeted for prevention. The SuprMam (suppressor of mammary tumour) breast cancer susceptibility alleles were previously identified as contributors to spontaneous mammary tumour...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
URI: http://hdl.handle.net/1885/172048
Source: Journal of Steroid Biochemistry and Molecular Biology
DOI: 10.1016/j.jsbmb.2018.12.004

Download

File Description SizeFormat Image
01_Ratnadiwakara_The_SuprMam1_breast_cancer_2019.pdf2.67 MBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator