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A metabolomic approach to dissecting osmotic stress in the wheat pathogen Stagonospora nodorum

Lowe, Rohan G T; Lord, Maryn; Rybak, Kasia; Trengove, Robert; Oliver, Richard Peter; Solomon, Peter


A non-targeted metabolomics approach was used to identify significant changes in metabolism upon exposure of the wheat pathogen Stagonospora nodorum to 0.5 M NaCl. The polyol arabitol, and to a lesser extent glycerol, was found to accumulate in response to the osmotic stress treatment. Amino acid synthesis was strongly down-regulated whilst mannitol levels were unaffected. A reverse genetic approach was undertaken to dissect the role of arabitol metabolism during salt stress. Strains of S....[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Fungal Genetics and Biology
DOI: 10.1016/j.fgb.2008.08.006


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