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Preparation of some angularly substituted and highly functionalized quinolizidines as building blocks for the synthesis of various alkaloids and related scaffolds of medicinal interest

Bissember, Alexander; Banwell, Martin

Description

The epimeric forms of the angularly substituted quinolizidine 6, representing potentially useful building blocks for the synthesis of various alkaloids, have been prepared via a pathway involving two consecutive ring-closing metathesis reactions. Variously hydroxy-protected derivatives (21, 22, and 26-29) of these compounds have also been generated.

dc.contributor.authorBissember, Alexander
dc.contributor.authorBanwell, Martin
dc.date.accessioned2015-12-07T22:13:38Z
dc.identifier.issn0040-4020
dc.identifier.urihttp://hdl.handle.net/1885/17097
dc.description.abstractThe epimeric forms of the angularly substituted quinolizidine 6, representing potentially useful building blocks for the synthesis of various alkaloids, have been prepared via a pathway involving two consecutive ring-closing metathesis reactions. Variously hydroxy-protected derivatives (21, 22, and 26-29) of these compounds have also been generated.
dc.publisherElsevier
dc.sourceTetrahedron
dc.subjectKeywords: alkaloid derivative; quinolizidine derivative; article; chemical analysis; chemical reaction; chemical structure; drug synthesis; priority journal; ring closing metathesis Alkaloids; Fasicularin; Quinolizidines; Ring-closing metathesis; Vinylation
dc.titlePreparation of some angularly substituted and highly functionalized quinolizidines as building blocks for the synthesis of various alkaloids and related scaffolds of medicinal interest
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume65
dc.date.issued2009
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationu2544221xPUB1
local.type.statusPublished Version
local.contributor.affiliationBissember, Alexander, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationBanwell, Martin, College of Physical and Mathematical Sciences, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue39
local.bibliographicCitation.startpage8222
local.bibliographicCitation.lastpage8230
local.identifier.doi10.1016/j.tet.2009.07.067
dc.date.updated2016-02-24T09:51:19Z
local.identifier.scopusID2-s2.0-69049116179
local.identifier.thomsonID000270121400022
CollectionsANU Research Publications

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