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An efficient visualization tool for the analysis of protein mutation matrices

David, Maria; Lapid, Carlo M; Daria, Vincent

Description

BACKGROUND It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce either wanted or unwanted effects, such as an increase or decrease in affinity, or a predisposition towards misfolding. Here, we describe a tool where such mutations are efficiently identified, categorized and visualized. To categorize the mutations, amino acids in a mutation matrix are arranged according to one of three...[Show more]

CollectionsANU Research Publications
Date published: 2008-04-28
Type: Journal article
URI: http://hdl.handle.net/1885/17065
Source: BMC Bioinformatics
DOI: 10.1186/1471-2105-9-218

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