Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis
The initiation of mammalian puberty and the maintenance of female reproductive cycles are events controlled by hypothalamic neurons that secrete the decapeptide gonadotropin-releasing hormone (GnRH). GnRH secretion is, in turn, controlled by changes in neuronal and glial inputs to GnRH-producing neurons. The hierarchical control of the process is unknown, but it requires coordinated regulation of these cell-cell interactions. Here we report the functional characterization of a gene (termed...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Clinical Investigation|
|01_Heger_Enhanced_at_puberty_1_(EAP1)_2007.pdf||Published Version||1.25 MB||Adobe PDF|
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