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Four-dimensional multi-site photolysis of caged neurotransmitters

Go, Mary Ann; To, Minh-Son; Stricker, Christian; Redman, Stephen; Bachor, Hans; Stuart, Greg; Daria, Vincent


Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in...[Show more]

CollectionsANU Research Publications
Date published: 2013-12-02
Type: Journal article
Source: Frontiers in Cellular Neuroscience
DOI: 10.3389/fncel.2013.00231
Access Rights: Open Access


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