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Optimizing interfacial features to regulate neural progenitor cells using polyelectrolyte multilayers and brain derived neurotrophic factor

Zhou, Kun; Sun, Gui Zhi; Bernard, Claude C.; Thouas, George A.; Nisbet, David R.; Forsythe, John S.

Description

The development of biomaterials with controllable interfacial features which have the capability to instruct cellular behavior are required to produce functional scaffolds for the treatment of spinal cord injury (SCI). Here, poly-ɛ-caprolactone surfaces were biofunctionalized via layer-by-layer (LbL) deposition. The polyelectrolytes employed in this LbL technique were heparin and poly-L-lysine (PLL), the latter being chosen to improve cell adhesion and the subsequent cellular function of in...[Show more]

CollectionsANU Research Publications
Date published: 2011-10-26
Type: Journal article
URI: http://hdl.handle.net/1885/16979
Source: Biointerphases
DOI: 10.1116/1.3656249

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