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Age-Related Differences in Plasma Proteins: How Plasma Proteins Change from Neonates to Adults

Ignjatovic, Vera; Lai, Cera; Summerhayes, Robyn; Mathesius, Ulrike; Tawfilis, Sherif; Perugini, Matthew A.; Monagle, Paul


The incidence of major diseases such as cardiovascular disease, thrombosis and cancer increases with age and is the major cause of mortality world-wide, with neonates and children somehow protected from such diseases of ageing. We hypothesized that there are major developmental differences in plasma proteins and that these contribute to age-related changes in the incidence of major diseases. We evaluated the human plasma proteome in healthy neonates, children and adults using the 2D-DIGE...[Show more]

CollectionsANU Research Publications
Date published: 2011-02-18
Type: Journal article
Source: PLoS ONE
DOI: 10.1371/journal.pone.0017213


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