Skip navigation
Skip navigation

Cognitive Deficits Are Associated with Frontal and Temporal Lobe White Matter Lesions in Middle-Aged Adults Living in the Community

Bunce, David; Cherbuin, Nicolas; Christensen, Helen; Wen, Wei; Sachdev, Perminder S.; Burns, Richard; Anstey, Kaarin


BACKGROUND The association between brain white matter lesions and cognitive impairment in old age is well established. However, little is known about this association in midlife. As this information will inform policy for early preventative healthcare initiatives, we investigated non-periventricular frontal, temporal, parietal and occipital lobe white matter hyperintensities (WMH) in relation to cognitive function in 428 (232 women) community-dwelling adults aged 44 to 48 years. RESULTS Frontal...[Show more]

CollectionsANU Research Publications
Date published: 2010-10-21
Type: Journal article
Source: PLoS ONE
DOI: 10.1371/journal.pone.0013567


File Description SizeFormat Image
01_Bunce_Cognitive_Deficits_Are_2010.pdfPublished Version206.21 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator