Skip navigation
Skip navigation

Evolutionary History and Attenuation of Myxoma Virus on Two Continents

Kerr, Peter J.; Ghedin, Elodie; DePasse, Jay V.; Fitch, Adam; Cattadori, Isabella M.; Hudson, Peter J.; Tscharke, David C.; Read, Andrew F.; Holmes, Edward C.

Description

The attenuation of myxoma virus (MYXV) following its introduction as a biological control into the European rabbit populations of Australia and Europe is the canonical study of the evolution of virulence. However, the evolutionary genetics of this profound change in host-pathogen relationship is unknown. We describe the genome-scale evolution of MYXV covering a range of virulence grades sampled over 49 years from the parallel Australian and European epidemics, including the high-virulence...[Show more]

CollectionsANU Research Publications
Date published: 2012-10-04
Type: Journal article
URI: http://hdl.handle.net/1885/16863
Source: PLoS Pathogens
DOI: 10.1371/journal.ppat.1002950

Download

File Description SizeFormat Image
01_Kerr_Evolutionary_History_and_2012.pdfPublished Version510.73 kBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator