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Global Analysis of Genetic, Epigenetic and Transcriptional Polymorphisms in Arabidopsis thaliana Using Whole Genome Tiling Arrays

Zhang, Xu; Shiu, Shinhan; Cal, Andrew; Borevitz, Justin O.


Whole genome tiling arrays provide a high resolution platform for profiling of genetic, epigenetic, and gene expression polymorphisms. In this study we surveyed natural genomic variation in cytosine methylation among Arabidopsis thaliana wild accessions Columbia (Col) and Vancouver (Van) by comparing hybridization intensity difference between genomic DNA digested with either methylation-sensitive (HpaII) or -insensitive (MspI) restriction enzyme. Single Feature Polymorphisms (SFPs) were assayed...[Show more]

CollectionsANU Research Publications
Date published: 2008-03-21
Type: Journal article
Source: PLoS Genetics
DOI: 10.1371/journal.pgen.1000032


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