The N-Terminal Intrinsically Disordered Domain of Mgm101p Is Localized to the Mitochondrial Nucleoid
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Hayward, David C.; Dosztányi, Zsuzsanna; Clark-Walker, George Desmond
Description
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core. Furthermore, there is a high level of amino acid sequence conservation in this region from widely diverse species. By contrast, the amino-terminal region, that is also essential for function, does not have recognizable conservation. Using a...[Show more]
Collections | ANU Research Publications |
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Date published: | 2013-02-13 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/16830 |
Source: | PLoS ONE |
DOI: | 10.1371/journal.pone.0056465 |
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01_Hayward_The_N-Terminal_Intrinsically_2013.pdf | Published Version | 718.73 kB | Adobe PDF |
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