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Synthesis of (±)-Panduratin A and Related Natural Products Using the High Pressure Diels-Alder Reaction

Pasfield, Luke A.; de la Cruz, Laura; Ho, Junming; Coote, Michelle; Otting, Gottfried; McLeod, Malcolm D.


Panduratin A and 4-hydroxypanduratin A are synthesised in 6 steps via a high pressure Diels-Alder reaction. This sequence has also allowed the synthesis of isopanduratin A, 4-hyrdoxyisopanduratin A, panduratin H, and panduratin I. In addition the regioselectivity of the Diels-Alder reaction has been investigated.

CollectionsANU Research Publications
Date published: 2013-01-04
Type: Journal article
Source: Asian Journal of Organic Chemistry
DOI: 10.1002/ajoc.201200171


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