Repurposing antiretroviral drugs for treating triple-negative breast cancer via LINE-1 regulation
The most common cancer in women is breast cancer with approximately 1 in 8 women developing this disease in their lifetime. Clinically, breast cancer can be divided into distinct subtypes based on the presence or absence of hormone receptors such as estrogen receptor (ER), progesterone receptor (PR) and expression of the HER2 gene. In this project, one of the most difficult to treat subclasses - triple negative (ER-/PR-/HER2-) breast cancer (TNBC) is studied. Until now, very limited drug...[Show more]
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