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Quantifying Embolism: Label-Free Volumetric Mapping of Thrombus Structure and Kinesis in a Microfluidic System with Optical Holography

He, Xuefei; Montague, Samantha; Gardiner, Elizabeth; Lee, W M Steve

Description

Embolization of thrombotic material may lead to acute events such as ischemia and myocardial infarction. The embolus is the physical detachment from a primary thrombus that has developed under fluid shear rates. The physical characteristics (surface area coverage, volume, mass, and packing density) of a thrombus influence the overall flow dynamics of an occluding blood vessel. Here, the effectiveness of holographic quantitative phase microscopy (QPM) in identifying multiple morphological...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
URI: http://hdl.handle.net/1885/164914
Source: Advanced Biosystems
DOI: 10.1002/adbi.201800089
Access Rights: Open Access

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