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Efficacy of anthelminthic drugs and drug combinations against soil-transmitted helminths: a systematic review and network meta-analysis

Clarke, Naomi; Doi, Suhail; Wangdi, Kinley; Chen, Yingxi; Clements, Archie; Vaz Nery, Susana

Description

Background: Periodic mass distribution of benzimidazole anthelminthic drugs is the key strategy to control soil-transmitted helminths (STH) globally. However, benzimidazoles have low efficacy against Trichuris trichiura, and there are concerns about benzimidazole resistance potentially emerging in humans. Therefore, identifying alternative drug regimens is a pressing priority. We present a systematic review and network meta-analysis, comparing the efficacy of 21 different anthelminthic drug...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
URI: http://hdl.handle.net/1885/164897
Source: Clinical Infectious Diseases
DOI: 10.1093/cid/ciy423

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