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Impact of Primary Tumor Site on Bevacizumab Efficacy in Metastatic Colorectal Cancer

Wong, Hui-li; Lee, Belinda; Field, Kathryn; Lomax, Anna; Tacey, Mark; Shapiro, Jeremy; McKendrick, J.; Zimet, Allan; Yip, Desmond; Nott, Louise M; Jennens, Ross R.; Richardson, Gary; Tie, J.; Kosmider, Suzanne; Parente, Phillip; Lim, Lionel; Cooray, Prasad; Tran, Ben; Desai, J.; Wong, Rachel; Gibbs, Peter


Background: With an ever-increasing focus on personalized medicine, all factors known to affect treatment response need to be considered when defining optimal therapy for individual patients. While the prognostic impact of primary tumor site on colorectal cancer (CRC) outcomes is established, emerging data suggest potential differences in response to biologic therapies. We studied the impact of tumor site on bevacizumab efficacy in patients with metastatic CRC. Patients and Methods: We analyzed...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
Source: Clinical Colorectal Cancer
DOI: 10.1016/j.clcc.2016.02.007


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