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Higher parental occupational social contact is associated with a reduced risk of incident pediatric type 1 diabetes: Mediation through molecular enteroviral indices

Ponsonby, Anne-Louise; Pezic, Angela; Cameron, Fergus; Rodda, Christine P; Kemp, Andrew; Carlin, John; Hyoty, Heikki; Sioofy-Khojine, Amirbabak; Dwyer, Terence; Ellis, Justine; Craig, Maria


We aimed to examine the association between parental occupational social contact and hygiene factors on type 1 diabetes (T1D) risk and possible mediation of these effects through child enteroviral infection. We interviewed 333 incident T1D cases and 660 controls from 2008-2011 in Melbourne, Australia. Enteroviral indices (ribonucleic acid by reverse transcription polymerase chain reaction and Coxsackie B virus antibody levels) in peripheral blood were measured in nested case control samples....[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: PLOS ONE
DOI: 10.1371/journal.pone.0193992
Access Rights: Open Access


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