Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis
Inflammasome signalling is an emerging pillar of innate immunity and has a central role in the regulation of gastrointestinal health and disease. Activation of the inflammasome complex mediates both the release of the pro-inflammatory cytokines IL-1β and IL-18 and the execution of a form of inflammatory cell death known as pyroptosis. In most cases, these mediators of inflammation provide protection against bacterial, viral and protozoal infections. However, unchecked inflammasome activities...[Show more]
|Collections||ANU Research Publications|
|Source:||Nature Reviews. Gastroenterology & Hepatology|
|s41575-018-0054-1.pdf||2.51 MB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.