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The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma

Katris, Nicholas J; van Dooren, Giel G; McMillan, Paul J; Hanssen, Eric; Tilley, Leann; Waller, Ross F

Description

The apical complex is the definitive cell structure of phylum Apicomplexa, and is the focus of the events of host cell penetration and the establishment of intracellular parasitism. Despite the importance of this structure, its molecular composition is relatively poorly known and few studies have experimentally tested its functions. We have characterized a novel Toxoplasma gondii protein, RNG2, that is located at the apical polar ring--the common structural element of apical complexes. During...[Show more]

CollectionsANU Research Publications
Date published: 2014-04-17
Type: Journal article
URI: http://hdl.handle.net/1885/16454
Source: PLoS Pathogens
DOI: 10.1371/journal.ppat.1004074

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