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Identification of MicroRNAs regulating the developmental pathways of bone marrow derived mast cells

Xiang, Yang; Eyers, Fiona; Young, Ian G.; Rosenberg, Helene F.; Foster, Paul S.; Yang, Ming


BACKGROUND MicroRNAs (miRNAs) play important roles in leukocyte differentiation, although those utilised for specific programs and key functions remain incompletely characterised. As a global approach to gain insights into the potential regulatory role of miRNA in mast cell differentiation we characterised expression in BM cultures from the initiation of differentiation. In cultures enriched in differentiating mast cells we characterised miRNA expression and identified miRNA targeting the mRNA...[Show more]

CollectionsANU Research Publications
Date published: 2014-05-21
Type: Journal article
Source: PLoS ONE
DOI: 10.1371/journal.pone.0098139


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